Cisdiamminedichloroplatinum

WebMar 1, 1979 · 1. Cisplatin is a co-ordination complex of a central platinum atom, two chlordies and two ammonia molecules in the “ cis ” position. 2. A prime mechanism of … WebCisplatin (cis-diamminedichloroplatinum) is an alkylating agent and a subset of platinum (II) analogs. It acts by producing an immensely reactive moiety that facilitates the cross …

Enhanced therapeutic effect of cis-diamminedichloroplatinum (II ...

WebA docetaxel-resistant prostate cell line (PC3DR2) was subsequently established using the same method (9); resistance-associated genes in this cell line were examined in the present study through DNA microarray, western blot analysis and reverse transcription-quantitative polymerase chain reaction (RT-qPCR). WebJan 1, 1987 · Abstract. Human ovarian cancer cell lines with stable cisplatin resistance have been developed by chronic exposure of the parent cisplatin-sensitive A2780 line to increasing concentrations of cisplatin. 2780CP8 (CP8 refers to this cell line's growth in medium containing 8 µm cisplatin) has several clonal cytogenetic abnormalities but lacks … how do you reduce radicals https://24shadylane.com

cis-Diamminedichloroplatinum(II): effects of a …

WebCisplatin Cl2H6N2Pt CID 5460033 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ... WebA regression rate of 12% (4/33) among patients with advanced upper aerodigestive carcinomas who received an intravenous regimen of cis‐diamminedichloroplatinum, … WebAbstract. Fifty patients with disseminated testicular cancer were treated with a three-drug combination consisting of cis-diamminedichloroplatinum, vinblastine, and bleomycin. … how do you reduce protein in urine

シスプラチン - Wikipedia

Category:cis-Diamminedichloroplatinum in the treatment of advanced …

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Cisdiamminedichloroplatinum

cis-Diamminedichloroplatinum in the treatment of advanced …

Webcis-Diamminedichloroplatinum(II): effects of a representative metal coordination complex on mammalian cells Pharmacol Ther. 1984;25(3):297-326.doi: 10.1016/0163-7258(84)90003-2. Author E B Douple PMID: 6542679 DOI: 10.1016/0163-7258(84)90003-2 No abstract available Publication types WebCis-diamminedichloroplatinum (II) (DDP) leads the series of platinum coordination complexes, a new class of cytotoxic agents. The antitumor and toxic effects of this drug …

Cisdiamminedichloroplatinum

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WebDec 3, 1979 · [Cis-diamminedichloroplatinum(II). A new antineoplastic agent derived from the group of heavy metal complexes (author's transl)] Platinum coordination complexes represent a new class of antineoplastic agents among which only cis-diamminedichloroplatinum(II) (cis-DDP) has undergone extensive clinical trials.

WebCisplatin (cisdiamminedichloroplatinum) for treatment of transitional cell carcinoma of the urinary bladder or urethra. J Vet Intern Med. May-Jun 1990;4(3):148-52.doi: 10.1111/j.1939-1676.1990.tb00888.x. Authors A S Moore 1 , A Cardona, W … WebA total of 26 patients with biopsy proved epidermoid carcinoma of the penis (Jackson stage III or IV) with measurable disease, no prior chemotherapy and adequate renal function received 50 mg. per M.2 cis-diamminedichloroplatinum intravenously on days 1 …

Webcis-Diamminedichloroplatinum (II) - Trait. This product is a crystalline powder of bright yellow to orange yellow; Odorless. This product is soluble in dimethyl sulfoxide, slightly … WebJun 1, 1975 · Summary. The effects of cis -diamminedichloroplatinum (NSC 119875) on murine and human hemopoietic precursor cells were studied in culture. When murine …

WebCis-diamminedichloroplatinum (II)-induced acute renal failure in the rat. Correlation of structural and functional alterations T. W. Jones, S. Chopra, J. S. Kaufman, W. …

WebDec 1, 1992 · To elucidate the mechanism of the synergistic cytotoxicity of 5-fluorouracil (5-FU) and cis-diamminedichloroplatinum (II) (CDDP), we studied the interaction of these agents using a human squamous carcinoma cell line (HST-1). how do you reduce swellingWeb1-β-D-Arabinofuranosylcytosine (ara-C) and hydroxyurea (HU) were investigated as possible inhibitors for the repair of cis-diamminedichloroplatinum(II) (DDP)-induced DNA damage. HU and ara-C were chosen for their known ability to … phone number for lufthansa usaWebJan 29, 1985 · Salmon sperm DNA, treated with the antitumor agent cis-diamminedichloroplatinum(II) (cis-DDP), was enzymatically degraded to … phone number for luxomeWebA comparative study was performed with a variety of human cell lines on the effects of treatments with cis-diamminedichloroplatinum (II) (cisplatin) on cell survival and the induction of unscheduled DNA synthesis. phone number for lutheran general hospitalWebSep 1, 1990 · The specific drug combination and experimental growth system for this introductory application was that of 1-β- d -arabinofuranosylcytosine (ara-C) and cisplatin with simultaneous drug exposure (1, 3, 6, 12, or 48 h) against L1210 leukemia in vitro. phone number for luvmehairシスプラチン(英語: cisplatin、略称:CDDP)は、白金錯体に分類される抗悪性腫瘍剤(抗がん剤)。シスプラチンの「シス」は、立体化学の用語のシスに由来する。錯体の中心金属は白金、配位子はアンミンと塩化物イオンであり、物質名はシス-ジアミンジクロロ白金(II)(cis-diamminedichloro-platinum(II)、cis-[PtCl2(NH3)2])である。なお、日光によって分解されるため、直射日光を避 … how do you reduce storage in icloudWebMay 15, 2015 · The interest in gold(III) as anticancer agent is a result of the current significance of the anticancer cisplatin, cis-diamminedichloroplatinum(II), [PtCl 2 (NH 3) 2] . Although cisplatin has been used for a long time for the treatment of different types of cancer there are several limitations and drawbacks. Gold(III) compounds provided ... phone number for luminess customer service